Liver test to aid paracetamol overdose treatment

People who overdose on paracetamol could be helped by a blood test that shows immediately if they are going to suffer liver damage. Researchers say the test – which detects levels of specific molecules in blood – will help doctors identify which patients arriving in hospital need more intense treatment. It will also help speed the development of new therapies for liver damage by targeting patients most likely to benefit. Full article.

Building for the future of Regenerative Medicine in Edinburgh

The CRM is marking the beginning of construction of the Centre of Tissue Repair. Together with the Centre of Regenerative Medicine, they will form the Institute for Regeneration and Repair.The Centre of Tissue Repair (CTR) is expected to be completed in 2020. With CRM the CTR will work to discover and deliver new therapies to repair tissue damage caused by disease and injury. Full Article.

UKRMP Niche Hub Researcher Wins Rosetrees Trust Interdiciplinary Prize

Dr James Dear from the University of Edinburgh has been announced as a joint winner of the 2017 Rosetrees Trust Interdisciplinary prize; the main aim of the prize is to promote collaborative research between medicine and engineering.  This funding will allow the development of a prototype device in collaboration with Dr Maiwenn Kersaudy-Kerhoas (Heriot-Watt University) to rapidly diagnose drug-induced liver damage based on the results from a UKRMP funded partnership project.

New study reveals cells can be reprogrammed to repair severe liver injury.

July 2017

The research shows bile duct cells can switch to become normal liver cells to help repair the liver after severe damage. Understanding how this back-up system is controlled could pave the way for new liver therapies. Full Article

UKRMP Researcher Awarded Runner-Up Prize at TERMIS Business Plan Competition

July 2017

Dr Kate Cameron from the Hay Group at the CRM, University of Edinburgh has been awarded the runner-up prize at the 2017 TERMIS Business Plan Competition in Davos, Switzerland. Full Article.

New Collaboration to Accelerate Drug Discovery Using Stem Cell Technology

The MRC-Centre for Regenerative Medicine (MRC-CRM) and the University of Dundee have announced a new collaboration to encourage partnership with the pharmaceutical industry. Please read more at the MRC CRM website.

UKRMP Niche Hub & Immunomodulation Hub Dragon’s Den – RESULTS!

01 Mar 2017

The UKRMP Niche Hub and UKRMP Immunomodulation Hub held a Dragons Den Commercialisation Workshop on Thursday 23rd February 2017 at the Centre for Stem Cells and Regenerative Medicine at KCL, London. The morning session included informative talks… Full Article

Invitation to join ‘Regeneration | Innovation @ MRC-CRM’, Monday 8th May 2017 (12.00-17.00 BST)

**Discover translational opportunities in Regenerative Medicine at the University of Edinburgh**

As Director of the MRC Centre of Regenerative Medicine I invite you to join us to explore opportunities for partnership and collaboration in the translation of our basic and clinical stem cell research into tools and treatments… Full Article

UKRMP Niche Hub & UKRMP Immunomodulation Hub Commercialisation Workshop Thursday 23rd February 2016.

10 Jan 2017

The UKRMP Niche Hub and the UKRMP Immunomodulation Hub are holding a Dragon’s Den event in London in February.

The main aim of the event is to provide advice from industry experts to help shape the translational and commercial opportunities for technologies being developed within the UKRMP Programme… Full Article

Registration open for 14-15 Nov 2016 Theo Murphy International Meeting.

12 Jul 2016

Organised by Hub member Dr Shukry Habib and his colleague Dr Paula Alexandre, this meeting is taking place 14-15 November 2016 at Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ… Full Article

New SAB member – Dr Mahendra Rao.

01 Jun 2016

It is my great pleasure to announce that Dr Mahendra Rao has accepted our invitation to become a member of our Hub’s Scientific Advisory Board, and has joined the SAB with immediate effect… Full Article

Identification of RSPO–LGR4/5–ZNRF3/RNF43 module as a master regulator of Wnt/Beta-catenin-mediated metabolic liver zonation.

28 Apr 2016

A paper in Nature Cell Biology co-authored by Niche Hub Director Stuart Forbes highlights the RSPO-LGR4/5-ZNRF3/RNF43 module as a master regulator of Wnt/beta-catenin-mediated metabolic liver zonation… Full Article

First UKRMP Researchers Retreat – March ’16, Manchester. 

23 Mar 2016

Organised by the UKRMP Project Managers, this retreat brought together PDRAs, RAs and PhD Students from across the UKRMP Hubs for two days of workshops and networking opportunities at the Manchester Conference Centre… Full Article

 Visit to the National Phenotypic Screening Centre (NPSC). 

22 Mar 2016

On March 1st 2016 researchers of the UKRMP Niche Hub and the CCBN visited the facilities of the National Phenotypic Screening Centre (NPSC)  in Dundee to discuss options for collaborative research projects and screening platforms… Full Article

 Translating Raman Microscopy into Regenerative Medicine. 

25 Feb 2016

We have just hosted this event at SCRM building, which was very successful. We now have a much clearer idea of how to support the translation of Raman into the Regenerative Medicine field, and Marieke has already started looking into funding opportunities to facilitate this for the Niche Hub… Full Article

Public lecture, 17 Feb ’16, Dr Anna Williams and Prof David Lyons . 

11 Feb 2016

The third in the current series of QMRI public lectures “Let’s Talk About..Health”  is next week on Weds 17th Feb and will be given by Dr Anna Williams of the UKRMP Niche Hob and Prof David Lyons: “Multiple Sclerosis: success, challenges and hope”Full Article

Dr Anna Williams interviewed for ‘Ask our questions’ 

22 Jan 2016 is a social network for people with multiple sclerosis. They aim to create a positive, enabling community which empowers MSers to acknowledge their MS, rethink how to achieve their ambitions and get on with their lives.

Dr Anna Williams, Niche Hub researcher at The University of Edinburgh was interviewed by member and MS patient Claire… Full Article

From Asymmetric Stem Cell Division to Tissue Engineering. 

08 Jan 2016

As part of the Spotlight on KCL’s Centre for Stem Cells and Regenerative Medicine, RegMedNet Community Manager Alexandra Thompson speaks to Dr Shukry Habib. To read the interview, please click here.

Liver cell therapies closer as study reveals key to mass production. 

25 Nov 2015

Stem cell scientists have made a key find that aids the quest to produce therapies for patients with liver damage. They have developed a new technique for growing liver cells from stem cells that is cost-effective and could be adapted for mass production of clinical grade cells… Full Article

Research on brain and spinal cord cells by the ffrench-Constant group sheds light on myelin sheath regulation. 

11 Nov 2015

Much of the mammalian brain and spinal cord comprises axons wrapped by myelin sheaths, whose length determines speed of nerve conduction.  Bechler et al. overturn the long-held view that myelin sheath-forming oligodendrocytes are all the same… Full Article

Frequently Asked Question – Prof Stuart Forbes.

30 Sept 2015  Full Article and Answers

Immunity study signals new ways to treat liver failure.

9 Sept 2015

Patients with liver failure could benefit from a treatment that helps the immune system to combat infections linked to the condition, research led by UKRMP Niche Hub scientists suggests.

A study in mice has revealed that treatment with an immune-boosting molecule called CSF-1 helps to trigger the body’s natural defence mechanisms in the liver. Researchers say that if the therapy proves successful in patients, it could help those who are unsuitable for a liver transplant….. Full Article

Liver regrown from stem cells.

20 July 2015

Scientists have repaired a damaged liver in a mouse by transplanting stem cells grown in the laboratory. It is the first time researchers have restored function to a severely damaged liver in a living animal using stem cells. Their findings pave the way for cell-based therapies that could one day replace the need for liver transplants….. Full Article